Do narcoleptics lack dopamine?

Even while narcoleptics don't "lack" dopamine per se, the disorder is caused by abnormalities in a number of neurotransmitters, including dopamine. Because dopamine regulates alertness and concentration, narcoleptics may have symptoms including trouble focusing or staying awake. Excessive daytime drowsiness and cognitive impairment are indications of an orexin deficit that might indirectly impact dopamine systems. Narcoleptics can stay more awake during the day with the use of medications like Modalert 200mg, which work by raising dopamine levels and encouraging alertness.